Supercard has released their newest client update for all of their slot 2 carts.  Here is the changelog, word-for-word from the official readme:

1. Fixed: 2253/2421 cant work
2. Fixed: some games which likes 2392 cant work
3. Fixed: the save size of 2385 fixed into 64Mbits

What u sai?

Bascally it translates to: Problems with Trauma Center 2, Diagasso, and other games have been fixed

For download specific to you system head over to the official supercard site:

HERE